Cortical pathology in multiple sclerosis patients with epilepsy:
source: J Neurol Neurosurg Psychiatry. 2011 Sep 2. [Epub ahead of print]
It is well known that epilepsy occurs more frequently in people with MS than in the general population. (Mean prevalence in MS 2.3% and in general population ranges between 0.27 and 1.7%). Seizures have often been the only or first manifestation of MS.
In this study RRMS patients with epilepsy were found to have a higher number of cortical lesions and a decreased cortical thickness than those without epilepsy. Epilepsy in this subgroup seems to be consequence of rapidly
evolving cortical pathology – both in terms of number of lesions and cortical atrophy. This subgroup of patients was also seen to have a higher degree of cognitive impairment and more physical disability.
This study shows that this subgroup of RRMS patients constitutes a group of MS patients whose cortical pathology needs further investigation.
This may be frustrating to hear beacuse it says lets look at it but hasn’t done it yet. Clearly these things need to have this initial study first to find out if there’s anything worth investigating and now that there is they neeed to find funding to take it further.
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Tags:cortical lesions,epilepsy,ms patients
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